USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P06702 USC-OGP 2-DE database:  P06702 P06702 General information about the entry View entry in simple text format Entry name S10A9_HUMAN Primary accession number P06702 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Protein S100-A9; AltName: Full=Calgranulin-B; AltName: Full=Calprotectin L1H subunit; AltName: Full=Leukocyte L1 complex heavy chain; AltName: Full=Migration inhibitory factor-related protein 14; Short=MRP-14; Short=p14; AltName: Full=S100 calcium-binding protein A9;. Gene name Name=S100A9 Synonyms=CAGB, CFAG, MRP14 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0531: pI=5.73; Mw=24807 Cross-references UniProtKB/Swiss-Prot P06702; S10A9_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name S10A9_HUMAN Primary accession number P06702 Secondary accession number(s) D3DV36 Q6FGA1 Q9NYM0 Q9UCJ1 Sequence was last modified on  January 1, 1988 (version 1) Annotations were last modified on  March 15, 2017 (version 194) Name and origin of the protein Description RecName: Full=Protein S100-A9; AltName: Full=Calgranulin-B; AltName: Full=Calprotectin L1H subunit; AltName: Full=Leukocyte L1 complex heavy chain; AltName: Full=Migration inhibitory factor-related protein 14; Short=MRP-14; Short=p14; AltName: Full=S100 calcium-binding protein A9; Gene name Name=S100A9 Synonyms=CAGB, CFAG, MRP14 Encoded on Name=S100A9; Synonyms=CAGB, CFAG, MRP14 Keywords 3D-structure; Antimicrobial; Antioxidant; Apoptosis; Autophagy; Calcium; Cell membrane; Chemotaxis; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Immunity; Inflammatory response; Innate immunity; Membrane; Metal-binding; Methylation; Phosphoprotein; Polymorphism; Reference proteome; Repeat; S-nitrosylation; Secreted; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X06233; CAA29579.1; -; mRNA EMBL M21064; AAA36326.1; -; Genomic_DNA EMBL M26311; AAA68480.1; -; mRNA EMBL AF237581; AAF62536.1; -; Genomic_DNA EMBL AF237582; AAF62537.1; -; Genomic_DNA EMBL CR542207; CAG47003.1; -; mRNA EMBL CR542224; CAG47020.1; -; mRNA EMBL AL591704; CAI19494.1; -; Genomic_DNA EMBL CH471121; EAW53333.1; -; Genomic_DNA EMBL CH471121; EAW53334.1; -; Genomic_DNA EMBL BC047681; AAH47681.1; -; mRNA CCDS CCDS1036.1; -; . PIR B31848; B31848; . RefSeq NP_002956.1; NM_002965.3; . UniGene Hs.112405; -; . PDB 1IRJ; X-ray; 2.10 A; A/B/C/D/E/F/G/H=2-114 PDB 1XK4; X-ray; 1.80 A; C/D/G/H/K/L=2-114 PDB 4GGF; X-ray; 1.60 A; C/L/T/V=1-114 PDB 4XJK; X-ray; 1.76 A; B/D/F/H/J=1-114 PDB 5I8N; NMR; -; A/B=1-114 PDBsum 1IRJ; -; . PDBsum 1XK4; -; . PDBsum 4GGF; -; . PDBsum 4XJK; -; . PDBsum 5I8N; -; . ProteinModelPortal P06702; -; . SMR P06702; -; . BioGrid 112188; 97; . DIP DIP-1166N; -; . IntAct P06702; 26; . MINT MINT-5002390; -; . STRING 9606.ENSP00000357727; -; . iPTMnet P06702; -; . PhosphoSitePlus P06702; -; . SwissPalm P06702; -; . BioMuta S100A9; -; . DMDM 115444; -; . OGP P06702; -; . SWISS-2DPAGE P06702; -; . UCD-2DPAGE P06702; -; . EPD P06702; -; . MaxQB P06702; -; . PaxDb P06702; -; . PeptideAtlas P06702; -; . PRIDE P06702; -; . TopDownProteomics P06702; -; . Ensembl ENST00000368738; ENSP00000357727; ENSG00000163220; . GeneID 6280; -; . KEGG hsa:6280; -; . UCSC uc001fbq.3; human; . CTD 6280; -; . DisGeNET 6280; -; . GeneCards S100A9; -; . HGNC HGNC:10499; S100A9; . HPA CAB009441; -; . HPA HPA004193; -; . MIM 123886; gene; . neXtProt NX_P06702; -; . OpenTargets ENSG00000163220; -; . PharmGKB PA34911; -; . eggNOG ENOG410J1XC; Eukaryota; . eggNOG ENOG4111C30; LUCA; . GeneTree ENSGT00760000119034; -; . HOGENOM HOG000246968; -; . HOVERGEN HBG001479; -; . InParanoid P06702; -; . KO K21128; -; . OMA DHIMEDL; -; . OrthoDB EOG091G12NB; -; . PhylomeDB P06702; -; . TreeFam TF332727; -; . Reactome R-HSA-5686938; Regulation of TLR by endogenous ligand; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-6799990; Metal sequestration by antimicrobial proteins; . ChiTaRS S100A9; human; . EvolutionaryTrace P06702; -; . GeneWiki S100A9; -; . GenomeRNAi 6280; -; . PRO PR:P06702; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000163220; -; . CleanEx HS_S100A9; -; . Genevisible P06702; HS; . GO GO:0030054; C:cell junction; IDA:HPA; . GO GO:0005856; C:cytoskeleton; TAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0005576; C:extracellular region; TAS:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; TAS:UniProtKB; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW; . GO GO:0050544; F:arachidonic acid binding; TAS:UniProtKB; . GO GO:0005509; F:calcium ion binding; TAS:UniProtKB; . GO GO:0008017; F:microtubule binding; TAS:UniProtKB; . GO GO:0050786; F:RAGE receptor binding; TAS:UniProtKB; . GO GO:0004871; F:signal transducer activity; TAS:ProtInc; . GO GO:0035662; F:Toll-like receptor 4 binding; TAS:UniProtKB; . GO GO:0008270; F:zinc ion binding; TAS:UniProtKB; . GO GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl; . GO GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB; . GO GO:0019730; P:antimicrobial humoral response; TAS:Reactome; . GO GO:0006915; P:apoptotic process; IEA:UniProtKB-KW; . GO GO:0014002; P:astrocyte development; IEA:Ensembl; . GO GO:0006914; P:autophagy; IDA:UniProtKB; . GO GO:0007267; P:cell-cell signaling; TAS:ProtInc; . GO GO:0032602; P:chemokine production; TAS:UniProtKB; . GO GO:0001816; P:cytokine production; TAS:UniProtKB; . GO GO:0042742; P:defense response to bacterium; TAS:UniProtKB; . GO GO:0050832; P:defense response to fungus; TAS:UniProtKB; . GO GO:0006954; P:inflammatory response; TAS:ProtInc; . GO GO:0045087; P:innate immune response; IEA:UniProtKB-KW; . GO GO:0002523; P:leukocyte migration involved in inflammatory response; IDA:UniProtKB; . GO GO:0070488; P:neutrophil aggregation; IDA:UniProtKB; . GO GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0035606; P:peptidyl-cysteine S-trans-nitrosylation; IDA:UniProtKB; . GO GO:0030194; P:positive regulation of blood coagulation; IEA:Ensembl; . GO GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB; . GO GO:0050729; P:positive regulation of inflammatory response; IDA:UniProtKB; . GO GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB; . GO GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB; . GO GO:0002793; P:positive regulation of peptide secretion; IEA:Ensembl; . GO GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB; . GO GO:0045113; P:regulation of integrin biosynthetic process; IEA:Ensembl; . GO GO:0006417; P:regulation of translation; IEA:Ensembl; . GO GO:0032119; P:sequestering of zinc ion; TAS:UniProtKB; . GO GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome; . Gene3D 1.10.238.10; -; 1; . InterPro IPR011992; EF-hand-dom_pair; . InterPro IPR018247; EF_Hand_1_Ca_BS; . InterPro IPR002048; EF_hand_dom; . InterPro IPR028475; S100-A9; . InterPro IPR001751; S100/CaBP-9k_CS; . InterPro IPR013787; S100_Ca-bd_sub; . PANTHER PTHR11639:SF110; PTHR11639:SF110; 1; . Pfam PF01023; S_100; 1; . SMART SM00054; EFh; 1; . SMART SM01394; S_100; 1; . SUPFAM SSF47473; SSF47473; 1; . PROSITE PS00018; EF_HAND_1; 1; . PROSITE PS50222; EF_HAND_2; 1; . PROSITE PS00303; S100_CABP; 1; .

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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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